Field-induced Dielectrophoresis and Phase Separation for Manipulating Particles in Microfluidics

نویسندگان

  • D. J. Bennett
  • B. Khusid
  • C. D. James
  • P. C. Galambos
  • M. Okandan
  • D. Jacqmin
  • A. Kumar
  • Z. Qiu
  • A. Acrivos
چکیده

We report observations of a new electric fieldand shear-induced many-body phenomenon in the behavior of suspensions. Its origin is dielectrophoresis accompanied by the field-induced phase separation. As a result, a suspension undergoes a field-driven phase separation leading to the formation of a distinct boundary between regions enriched with and depleted of particles. The theoretical predictions are consistent with experimental data even though the model contains no fitting parameters. It is demonstrated that the field-induced dielectrophoresis accompanied by the phase separation provides a new method for concentrating particles in focused regions and for separating biological and non-biological materials, a critical step in the development of miniaturizing biological assays.

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تاریخ انتشار 2004